Table 3 Basic information of patients with different miR-146a rs2910164 genotypes

Age, y

57.07 ± 11.41

59.22 ± 10.81*

59.01 ± 9.63

Male, n (%)

192(84.2)

243(82.9)

72(79.1)

Smoking, n (%)

138(60.5)

187(63.8)

60(65.9)

Hypertension, n (%)

107(46.9)

140(47.8)

48(52.7)

Diabetes mellitus, n (%)

43(18.9)

44(15.0)

12(13.2)

Family history, n (%)

13(5.7)

16(5.5)

11(12.1)

SBP, mmHg

123.72 ± 19.19

126.47 ± 23.40

125.85 ± 22.31

DBP, mmHg

78.13 ± 11.96

78.86 ± 14.52

77.34 ± 12.53

Heart rate, bmp

74.19 ± 12.06

75.02 ± 16.41

75.92 ± 14.74

LVEF, %

56.32 ± 11.51

56.84 ± 11.46

56.44 ± 11.04

Creatinine, mg/dl

81.16 ± 20.37

79.12 ± 24.60

78.08 ± 21.11

FBG, mmol/l

7.67 ± 3.46

7.12 ± 3.02

7.82 ± 3.49

UA, μmol/l

315.08 ± 92.79

320.13 ± 91.82

313.51 ± 118.39

FIB, g/l

3.58 ± 1.33

3.53 ± 1.42

3.86 ± 1.46^#

D-Dimer, mg/l (IQR)

0.80(0.65)

0.79(0.80)

0.85(0.83)

CRP, μg/ml(IQR)

2.28(5.55)

1.82(5.49)

1.90(6.19)

BNP, ng/l(IQR)

275.90(936.23)

163.30(889.97)

164.3 (850.23)

TC, mmol/l

4.01 ± 0.99

4.02 ± 1.05

4.22 ± 1.13

TG, mmol/l

1.68 ± 0.94

1.67 ± 1.13

1.59 ± 1.01

HDLC, mmol/l

1.01 ± 0.24

0.98 ± 0.25

1.02 ± 0.22

LDLC, mmol/l

2.33 ± 0.73

2.38 ± 0.82

2.51 ± 0.95

ApoA1, g/l

1.05 ± 0.20

1.04 ± 0.22

1.65 ± 0.57

ApoB, g/l

0.77 ± 0.23

0.80 ± 0.30

0.83 ± 0.30

Lpa, mg/dl

184.75 ± 176.93

187.86 ± 150.28

225.60 ± 189.41*

ACEI, n (%)

206(90.3)

264(90.1)

84(92.3)

β-blocker, n (%)

201(88.2)

250(85.3)

85(93.4)

Statin, n (%)

217(95.2)

281(95.9)

81(89.0)