Table 2 Association of miRNA polymorphisms with ACS Risk
|  | Control (n = 552) | ACS (n = 619) | χ2 | OR (95% CI) | P Value |
|---|---|---|---|---|---|
miR146aC > G | |||||
 CC | 216 (39.13%) | 208 (33.60%) |  | 1.000 (reference) |  |
 CG | 263 (47.64%) | 302 (48.79%) | 1.873(vs. CC) | 1.192 (0.927–1.534) | 0.171 |
 GG | 73 (13.23%) | 109 (17.61%) | 5.991 (vs. CC) | 1.551 (1.090–2.205) | 0.014 |
Dominant model (CC vs. CG + GG) | 3.860 | 1.270(1.000–1.613) | 0.049 | ||
Recessive model (CC + CG vs. GG) | 4.273 | 1.402 (1.017–1.934) | 0.039 | ||
HWE χ2 | 0.254 | 0.001 |  |  |  |
HWE p | 0.614 | 0.975 | Â | Â | Â |
miR34bT > C | |||||
 TT | 245 (44.38%) | 291 (47.01%) |  | 1.000 (reference) |  |
 TC | 251 (45.47%) | 279 (45.07%) | 0.291(vs. TT) | 0.936 (0.736 -1.191) | 0.589 |
 CC | 56 (10.15%) | 49 (7.92%) | 2.049(vs. TT) | 0.737 (0.484 -1.121) | 0.152 |
Dominant model (TT vs. CT + CC) |  | 0.811 | 0.900 (0.714–1.133) | 0.368 | |
Recessive model (TT + CT vs. CC) |  | 1.776 | 0.761(0.509–1.138) | 0.183 | |
HWE χ2 | 0.503 | 2.543 |  |  |  |
HWE p | 0.478 | 0.111 | Â | Â | Â |