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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: MiR-146a rs2910164 (G/C) polymorphism is associated with the development and prognosis of acute coronary syndromes: an observational study including case control and validation cohort

Fig. 1

MiR-146a and miR-34b are highly expressed in CAD patients. A Principal component analysis (PCA) of GSE64566 dataset from the NCBI_GEO database (https://www.ncbi.nlm.nih.gov/gds/); B Volcano plot. Red represents up-regulated genes; blue represents down-regulated genes; black represents genes with no significant difference in expression, each point in the figure represents a gene, and the screened differential genes are genes within the range of p-value < 0.05, |FC|> 1.2; C Heatmap. Each small square in the figure represents 1 gene in 1 sample, and its color represents the expression value of the gene. The darker the color, the higher the gene expression level (red for up-regulated genes, blue for down-regulated genes). Differentially expressed genes with p-value < 0.05 and |FC|≥ 1.2 are shown in the figure; D, E. Boxplot of miR-146a and miR-34b expression

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Journal of Translational Medicine

ISSN: 1479-5876

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