Fig.6
From: CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer
Decreased CEBPG inhibited OC progression at least partly through suppression of SLC7A11 both in vitro and in vivo. Colony formation A and B and growth C and D of CEBPG-decreased A2780 and Hey cells, with or without SLC7A11 reexpression, were measured. Scale bar: 100 μm. E–H The migration and invasion assays of OC cell lines, with or without SLC7A11 reexpression, were analyzed, Scale bar: 50 μm. I CEBPG-knockdown A2780 cells, with or without SLC7A11 reexpression, were subcutaneously injected into the ovaries of nude mice. Images of orthotopic ovarian tumors in mice. J Pictures of the removed tumors. K Luciferase expression was detected in model mice. L Analysis of tumor weight in the two groups. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns: no significance