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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Preventative effect of TSPO ligands on mixed antibody-mediated rejection through a Mitochondria-mediated metabolic disorder

Fig. 4

TSPO ligands attenuate DSA-mediated injury and prolong the survival of cardiac allografts. A Experimental protocol of creation of a model of antibody-mediated cardiac allograft rejection. B Survival curve of a cardiac allograft. Representative images of (C) hematoxylin and eosin (H and E), (D) TUNEL, and C4d (E) staining of cardiac allografts 4 days after cardiac transplantation. F Average Optical Density (AOD) of C4d staining. G Circulating levels of DSAs, IgG, and IgM were determined by flow cytometry (n = 5). E *P < 0.05; **P < 0.01

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