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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression

Fig. 8

Validation of USP37 interaction with PCNA using molecular docking. A Structure model of full-length USP37 label with its domains. B USP7 PH domain docked with PCNA-DNA complex and the superimposition of trimeric PCNA-DNA-USP37 complex before and after 100 ns MD simulations. C The surface potential of PCNA and USP37 with DNA. D The interactions formed by USP37 (magenta) with PCNA (green) and DNA

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