Fig. 6

The preserved mitochondrial integrity by NRP-1 overexpression after tMCAO. A Representative immunoblots and B Western Blot analysis of mitochondrial Cyt c, C Cytosolic Cyt c, D Nuclear AIF in the penumbra region of different groups; n = 4. Data are expressed as mean ± SEM. and analyzed by one-way analysis of ANOVA with Bonferroni’s post hoc test. **p < 0.01, ***p < 0.001, as compared with the Sham group; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, as compared with the tMCAO + AAV-empty group. E Representative immunofluorescence image of Cyt c in the cortex of different groups. Scale bar: 20 μm