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Table 2 Correlation between AURKA mRNA level and clinical characteristics in BLCA patients

From: STIL/AURKA axis promotes cell proliferation by influencing primary cilia formation in bladder cancer

 

AURKA expression

High expression

Low expression

Total

χ2

P value

Gender

 Female

23 (28.0%)

7 (8.4%)

30 (18.2%)

9.3906

0.002181

 Male

59 (72.0%)

76 (91.6%)

135 (81.8%)

  

Age

 < 60

18 (22.0%)

28 (33.7%)

46 (27.9%)

2.2927

0.13

 ≥60

64 (78.0%)

55 (66.3%)

119 (72.1%)

  

Pathologic T

 Ta

5 (6.1%)

19 (22.9%)

24 (14.5%)

28.901

8.186e-06

 T1

33 (40.2%)

47 (56.6%)

80 (48.5%)

  

 T2

18 (22.0%)

13 (15.7%)

31 (18.8%)

  

 T3

18 (22.0%)

1 (1.2%)

19 (11.5%)

  

 T4

8 (9.8%)

3 (3.6%)

11 (6.7%)

  

Pathologic N

 N0

68 (82.9%)

81 (97.6%)

149 (90.3%)

8.5232

0.003506

 N1-3/Nx

14 (17.1%)

2 (2.4%)

16 (9.7%)

  

Pathologic M

 M0

78 (95.1%)

80 (96.4%)

158 (95.8%)

0.00026852

0.9869

 M1

4 (4.9%)

3 (3.6%)

7 (4.2%)

  

Grade

 High grade

51 (62.2%)

9 (10.8%)

60 (36.4%)

44.812

2.169e-11

 Low grade

31 (37.8%)

74 (89.2%)

105 (63.6%)

  

Invasiveness

 No

37 (45.1%)

66 (79.5%)

103 (62.4%)

19.364

1.08e-05

 Yes

45 (54.9%)

17 (20.5%)

62 (37.6%)

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