Integrated microbiome and metabolome analysis reveals novel urinary microenvironmental signatures in interstitial cystitis/bladder pain syndrome patients

Table 1 Demographic characteristics and symptom scores of IC/BPS and control groups

Characteristics	IC/BPS group (n = 30)	Control group (n = 30)	P-value
Sex			0.79
Male	11	10
Female	19	20
Age	40.07 ± 12.96	39.13 ± 13.24	0.78
BMI	20.83 ± 2.44	22.87 ± 3.05	< 0.01
Marital status			0.35
Unmarried	5	8
Married	25	22
Fertility status			0.77
No children	7	8
One or more children	23	22
Smoking			0.32
Presence	7	4
Absence	23	26
VAS	2.40 ± 0.86	0.30 ± 0.47	< 0.01
PUF	16.70 ± 4.10	4.33 ± 1.49	< 0.01
ICSI	13.80 ± 2.01	1.87 ± 0.86	< 0.01
ICPI	11.37 ± 1.63	1.57 ± 0.97	< 0.01
SDS	53.23 ± 3.79	40.27 ± 3.87	< 0.01
SAS	54.20 ± 4.60	41.78 ± 4.20	< 0.01

BMI: Body Mass Index, VAS: Visual Analogue Scale for Pain, PUF: Patient Symptom Questionnaire for Pelvic Pain, Urgency and Frequency, ICSI: Interstitial Cystitis Symptom Index, ICPI: Interstitial Cystitis Problem Index, SDS: Self-Rating Depression Scale, a standard score greater than 53 is considered depression, 53-62 is mild depression, 63-72 is moderate depression, and more than 72 is severe depression, SAS: Self-Rating Anxiety Scale, a standard score greater than 50 is considered anxiety, 50-60 is mild anxiety, 61-70 is moderate anxiety, and 70 or more is severe anxiety

ISSN: 1479-5876