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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2

Fig. 1

Correlation between ILA, IAA, IAld levels with intestinal I/R injury. A-C The level of ILA (A), IAA (B), IAld (C) in cecal contents from the sham mice and mice undergoing intestinal I/R injury (n = 4). D-F Correlation analysis between preoperatively fecal contents of ILA (D), IAA (E), IAld (F) levels and LIFE score in CPB surgery patients (n = 12). G-I Correlation analysis between preoperatively fecal contents of ILA (G), IAA (H), IAld (I) levels and serum I-FABP levels of patients after surgery (T1) as compared to preoperatively (T0) (n = 12). J-L Correlation analysis between pre-operative fecal content of ILA (J), IAA (K), IAld (L) levels and serum D-lactate levels of patients after surgery (T1) as compared to preoperatively (T0) (n = 12). Results were presented as mean ± SEM. The statistical tests used included: two-tailed student’s t-test in A–C and Spearman’s correlation coefficients in D–L. ** p < 0.01

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