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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants

Fig. 1

MTAG results of IBS and overlap with previous GWAS on IBS, neuroticism, depression and anxiety. a Z-scores of MTAG-IBS and original GWAS on IBS, neuroticism, depression and anxiety for each of the independent lead SNPs (n = 42) found in MTAG-IBS results. Dotted grey line indicates 0 Z-score and solid grey lines indicate statistical significance at P < 5-E08. b Manhattan plot of the MTAG-IBS results. Dotted grey line indicates statistical significance at P < 5-E08. c QQ plot of the MTAG-IBS results. d Venn diagram depicting overlap among MTAG-IBS independent lead SNPs and genome-wide significant SNPs in the original GWAS

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