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Table 2 TMB of nuclear genomes in tumor tissues between mutated and non-mutated genes

From: Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma

Gene name

P value*

Number of samples with somatic mutations

RYR2

< 0.001

5

SI

< 0.01

4

RYR3

< 0.01

5

TP53

< 0.01

12

USH2A

< 0.01

3

NRXN1

< 0.01

4

FLG

< 0.05

3

TTN

< 0.05

13

ZFHX4

< 0.05

2

LRP1B

< 0.05

5

SPTA1

< 0.05

2

ABCA13

< 0.05

2

RET

< 0.05

2

ZNF831

< 0.05

3

PCDH15

< 0.05

2

GRIN2B

< 0.05

2

CSMD3

< 0.05

2

SYNE2

< 0.05

2

  1. *Wilcoxon signed rank test compared TMB between different groups