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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma

Fig. 8

Mutation landscape of mitochondrial genome in cfDNA from plasma samples of Stage IA LUAD patients. The mutation landscape of A all the genes in the mitochondrial genome from 27 plasma samples of Stage IA LUAD patients, and B all the top five mutated genes in the mitochondrial genome from 27 plasma samples of Stage IA LUAD patients. The outer circle showed the SNVs of the top mutated genes in 27 plasma samples. The inner circle displayed the INDELs of the top mutated genes in 27 plasma samples. C The TMB between the tumor tissues with and without mutations in all the genes in the mitochondrial genome (**p < 0.01; *p < 0.05)

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