Fig. 7

Mutation landscape of nuclear genome in cfDNA from plasma samples of Stage IA LUAD patients. A The mutation landscape of all the mitochondrial genome genes from 32 plasma samples of Stage IA LUAD patients. Top: the TMB between the cfDNA from plasma samples with and without mutations. Bottom: the maximum VAF for each gene in 32 plasma samples of Stage IA LUAD patients. The TMB between the cfDNA from plasma samples with and without mutations in B MAGEC1 (p < 0.01), C ZNF208 (p < 0.01), D PCLO (p < 0.01), E TTN (p < 0.01), and F AHNAK2 (p < 0.05)