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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma

Fig. 3

Mutation landscape of nuclear genome in tumor tissues of Stage IA LUAD patients. A The mutation landscape of 115 genes in the nuclear genome from 43 tumor tissues of Stage IA LUAD patients. Top: the TMB between the tumor tissues with and without mutations. Bottom: the maximum VAF for each gene in 43 tumor tissues of Stage IA LUAD patients. The TMB between the tumor tissues with and without mutations in B RYR2 (p < 0.001), C RYR3 (p < 0.001), D TP53 (p < 0.01), E TTN (p < 0.05), and F LRP1B (p < 0.05) (***p < 0.001; **p < 0.01; *p < 0.05)

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