Fig. 4

Candidate cfRNAs for predicting preterm birth. A Heatmap showing expression level in each samples of candidate genes in plasma and placental RNA-seq datasets (plasma samples: seven FTB vs. eight PTB, placenta samples: 31 FTB vs. 31 PTB). B Correlation heatmap displaying the inter connectivity among candidate genes. The size of the squares and the color scale correlate to the correlation of gene expression in RNA-seq data including plasma and placenta. left: plasma, right: placenta. C Expression level for differentially expressed genes in the discovery based on plasma cfRNA-seq datasets. D Expression level for differentially expressed genes in the discovery based on placental RNA-seq datasets. *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001