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Table 4 Clinicopathological characteristics of breast cancer patients of the validation cohort

From: Analysis of circulating extracellular vesicle derived microRNAs in breast cancer patients with obesity: a potential role for Let-7a

Clinical variables

Validation cohort (n)

NW (6) (BMI < 24.9 kg/m2)

OW/Ob (12) (BMI ≥ 25 kg/m2)

Age, y

 Median

50

64

 Range

34–73

46–83

 BMI Kg/m2, mean ± SD

23 ± 1.8

30.6 ± 3

Histology, %

 In situ ductal carcinoma

0

0

 Invasive ductal carcinoma

83

92

 Invasive lobular carcinoma

0

8

Grading, %

 Well differentiated (G1)

17

0.8

 Moderately differentiated (G2)

33

25

 Poor/undifferentiated (G3)

33

58

 Unknown

17

8.3

Menopausal status, %

 Premenopausal

50

17

 Postmenopausal

50

83

Estrogen receptor status, %

 Negative

17

25

 Positive (> 1%)

83

75

Progesterone receptor status, %

 Negative

33

33

 Positive (> 1%)

67

67

HER2/Neu status, %

 Negative

50

92

 Positive

33

8.3

Ki67, %

  < 14

33

8.3

  ≥ 14

67

92

  1. NW Normal weight, OW/Ob Overweight/Obese, BMI Body Mass Index, SD Standard Deviation, HER2/neu Human Epidermal Growth Factor 2