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Table 1 Clinicopathological characteristics of breast cancer patients with different BMI included in the screening cohort

From: Analysis of circulating extracellular vesicle derived microRNAs in breast cancer patients with obesity: a potential role for Let-7a

Clinical variables

Screening cohort (n)

NW (9) (BMI < 24.9 kg/m2)

OW/Ob (18) (BMI ≥ 25 kg/m2)

Age, y

 Median

44

55

 Range

30–73

36–76

 BMI Kg/m2, mean ± SD

21.7 ± 2.5

30.6 ± 4.06

Histology, %

 In situ ductal carcinoma

0

5.5

 Invasive ductal carcinoma

100

83.3

 Invasive lobular carcinoma

0

11.2

Grading, %

 Well differentiated (G1)

0

11.1

 Moderately differentiated (G2)

33.3

55.6

 Poor/undifferentiated (G3)

44.4

22.2

 Unknown

22.2

11.1

Menopausal status, %

 Premenopausal

88.8

50

 Postmenopausal

11.2

50

Estrogen receptor status, %

 Negative

22.2

5.5

 Positive (> 1%)

77.7

94.4

Progesterone receptor status, %

 Negative

22.2

22.2

 Positive (> 1%)

77.7

77.7

HER2/Neu status, %

 Negative

77.7

72.2

 Positive

22.2

27.7

Ki67, %

  < 14

0

11.2

  ≥ 14

100

88.8

  1. NW Normal weight, OW/Ob Overweight/Obese, BMI Body Mass Index, SD Standard Deviation, HER2/neu Human Epidermal Growth Factor 2