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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation

Fig. 7

A Gene expression analysis of the main transcription factors related to lymphocyte activation in Jurkat stably transfected cells. qRT-PCR analysis of BLIMP1a, BLIMP1b, GATA3, FOXP3, RORC, TBX21, BCL6, CD40LG, KLF2, CTLA4, IL2, IL2RA, CCR4, CCR6, and CXCR3 on Jurkat cells transfected with the plasmid encoding for RIZ1, RIZ2 or with pSG5 control vector and treated with or without treatment with polyclonal activators for 6 h. Three independent experiments in triplicates were performed and data expressed as mean ± SD. ns (not significant), *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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