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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Prospective, longitudinal analysis of the gut microbiome in patients with locally advanced rectal cancer predicts response to neoadjuvant concurrent chemoradiotherapy

Fig. 1

Changes in gut flora diversity and composition over the course of neoadjuvant concurrent chemoradiation therapy (nCCRT) for locally advanced rectal cancer. a, b, Bacterial α-diversity in the “good response” group (i.e., those with AJCC tumor regression grade [TRG] 0–1) and “poor response” group (AJCC TRG2-3) before, during, and after treatment, measured by the Shannon index (left) and the InvSimpson index (right) at the amplicon sequence variant (ASV) level (a) and the genus level (b). c, Changes in the abundance of the 20 most abundant genus-level microbes over time. *P < 0.05; **P < 0.01; ***P < 0.001

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