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Table 1 Characteristics of the study subjects with and without NAFLD

From: Lipid metabolism, BMI and the risk of nonalcoholic fatty liver disease in the general population: evidence from a mediation analysis

 

Non-NAFLD

NAFLD

Standardized difference (%)

P-value

No. of subjects

11,744

2507

  

Sex

  

78 (74, 83)

< 0.001

 Women

6362 (54.17%)

478 (19.07%)

 

< 0.001

 Men

5382 (45.83%)

2029 (80.93%)

 

< 0.001

Age, years

42.00 (18.00–79.00)

44.00 (19.00–72.00)

18 (13, 22)

< 0.001

Weight, kg

57.72 (9.98)

72.18 (11.33)

135 (131, 140)

< 0.001

Height, cm

164.11 (8.44)

168.03 (7.90)

48 (44, 52)

< 0.001

BMI, kg/m2

21.33 (2.61)

25.50 (3.13)

145 (140, 149)

< 0.001

WC, cm

74.09 (7.92)

85.98 (7.79)

151 (147, 156)

< 0.001

ALT, U/L

15.00 (2.00–856.00)

27.00 (6.00–220.00)

96 (91, 100)

< 0.001

AST, U/L

17.00 (3.00–590.00)

20.00 (6.00–140.00)

56 (51, 60)

< 0.001

GGT, U/L

14.00 (3.00–259.00)

23.00 (6.00–375.00)

61 (57, 66)

< 0.001

TC, mmol/L

5.06 (0.85)

5.44 (0.87)

45 (41, 49)

< 0.001

TG, mmol/L

0.65 (0.07–10.27)

1.24 (0.16–7.69)

96 (91, 100)

< 0.001

HDL-C, mmol/L

1.52 (0.40)

1.19 (0.29)

96 (92, 101)

< 0.001

LDL-C. mmol/L

2.95 (0.95–9.72)

3.49 (1.16–6.59)

68 (64, 73)

< 0.001

Non-HDL-C, mmol/L

3.47 (1.22–10.93)

4.25 (1.38–7.71)

83 (79, 88)

< 0.001

RC, mmol/L

0.50 (0.17–2.72)

0.71 (0.18–2.37)

107 (102, 111)

< 0.001

TC/HDL-C ratio

3.33 (1.51–13.02)

4.71 (1.59–10.75)

111 (106, 115)

< 0.001

TG/HDL-C ratio

0.43 (0.03–16.55)

1.07 (0.12–11.67)

92 (87, 96)

< 0.001

LDL-C/HDL-C ratio

1.99 (0.43–10.35)

3.04 (0.50–8.01)

106 (101, 110)

< 0.001

Non-HDL-C/HDL-C ratio

2.33 (0.51–12.02)

3.71 (0.59–9.75)

111 (106, 115)

< 0.001

RC/HDL-C

0.33 (0.07–4.39)

0.62 (0.09–3.57)

107 (103, 112)

< 0.001

FPG, mmol/L

5.09 (0.40)

5.39 (0.36)

78 (74, 82)

< 0.001

HbA1c, %

5.15 (0.31)

5.30 (0.33)

46 (42, 51)

< 0.001

SBP, mmHg

111.91 (14.02)

123.41 (14.83)

80 (75, 84)

< 0.001

DBP, mmHg

69.69 (9.85)

77.81 (10.19)

81 (77, 85)

< 0.001

Habit of exercise

2093 (17.82%)

377 (15.04%)

8 (3, 12)

< 0.001

Drinking status

  

4 (-0.01, 9)

0.162

 No or little

9717 (82.74%)

2088 (83.29%)

  

 Light

1472 (12.53%)

286 (11.41%)

  

 Moderate

555 (4.73%)

133 (5.31%)

  

Smoking status

  

35 (31, 39)

< 0.001

 None

7561 (64.38%)

1185 (47.27%)

  

 Former

1920 (16.35%)

639 (25.49%)

  

 Current

2263 (19.27%)

683 (27.24%)

  
  1. Values were expressed as mean (SD) or medians (quartile interval) or n (%). The differences between groups were compared by chi-square test or Mann–Whitney U test or t test (P-value < 0.05 indicates significance). Standardized difference values were used to evaluate and quantify the difference between groups (> 10% were considered significant)
  2. NAFLD: Nonalcoholic fatty liver disease; BMI: body mass index; WC: Waist circumference; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; HDL-C: high-density lipoprotein cholesterol; TC: total cholesterol; TG: triglyceride; LDL-C: low density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol; RC: remnant cholesterol; HbA1c: hemoglobin A1c; FPG: fasting plasma glucose; SBP: systolic blood pressure; DBP: diastolic blood pressure
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Journal of Translational Medicine

ISSN: 1479-5876

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