Fig. 7From: Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysisDifference of angiogenic effects of ABM and LBM macrophages. A DAPI (blue), Cd34 (green) immunofluorescence staining (scale bar, 100 μm). B Tube formation effect of macrophage CM on BMSCs (scale bar, 200 μm). C The plot of statistical analysis for numbers of meshes of BMSCs. D Tube formation effect of macrophage CM on ECs (scale bar, 100 μm). E The plot of statistical analysis for numbers of meshes of ECs. Data were expressed as mean ± SEM from 3 independent experiments. *Corrected P-value < 0.05. **Corrected P-value < 0.01. ABM alveolar bone marrow, LBM long bone marrow, CM conditioned medium, BMSC bone mesenchymal stem cells, EC endothelial cellBack to article page