Fig. 7

Severe peripheral inflammation promoted the CCR5/JAK2/STAT3/MMP9 signaling pathway 3 days after ICH. A–E Western blot images and quantitative analysis of CCR5, p-JAK2, p-STAT3, and MMP9 expression in the ipsilateral hemisphere in the sham, LPS, LPS + sham, ICH, and ICH + LPS groups 3 days after ICH. The data are expressed as the mean ± SD. ^# vs. the sham group, P < 0.05; ^a vs. the LPS group, P < 0.05; ^b vs. the LPS + sham group, P < 0.05; ^& vs. the ICH group, P < 0.05; ns: no significance