Fig. 5
From: EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway
EGR1 promoted migration and invasion ability via SNAI2-dependent EMT pathway in pancreatic cancer cells. A Overexpression of SNAI2 offset the effect of EGR1 knockdown on cell migration and invasion ability. B Knockdown of SNAI2 offset the effect of EGR1 overexpression on cell migration and invasion ability. C Representative images of immunofluorescence staining showed the fluorescence of E-cadherin and nucleus after corresponding processing. D Column chart of the fluorescence intensity of E-cadherin corresponding to figure C. E The expression of EMT-related proteins by western blot after EGR1 knockdown and SNAI2 overexpression in BxPC-3 or EGR1 overexpression and SNAI2 knockdown in PANC1. *: p < 0.05; ***: p < 0.001