Fig. 7From: Tuning CARs: recent advances in modulating chimeric antigen receptor (CAR) T cell activity for improved safety, efficacy, and flexibilityThe schematic of two-component adaptor CAR platforms. The soluble adaptor or antigen recognition molecule (component 2) binds to the transmembrane receptor (component 1) at the surface of the engineered T cells to form a functional CAR activating T cell effector functionsBack to article page