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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: miRNA-seq identification and clinical validation of CD138+ and circulating miR-25 in treatment response of multiple myeloma

Fig. 8

Circulating miR-25 is associated with aggressive disease phenotype and poor survival. AD Box plots presenting the correlation of plasma miR-25 levels with R-ISS stage A, high risk cytogenetics B B2M levels C and creatinine levels D in the screening MM cohort. p-values calculated by Kruskal–Wallis test A and Mann–Whitney U test BD. E Kaplan–Meier survival curves for overall survival (OS) of the MM screening cohort. p-value calculated by log-rank test. Forest plot of the univariate F Cox proportional regression analysis. Internal validation was performed by bootstrap analysis based on 1000 bootstrap samples. HR: Hazard Ratio, 95% CI: 95% confidence interval of the estimated HR

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