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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury

Fig. 2

TREM-1 activation triggers macrophage necroptosis dependently on RIPK3. A The cell survival rate was examined by CCK‐8, n = 5. BD p-RIPK3ser232, RIPK3, p-MLKLser345, and MLKL protein, n = 3. E Immunofluorescence staining for MLKL (green); scale bars = 5 μm. F TNF‐α production in the supernatant. G, H IL-1β p17 level in the supernatant

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