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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway

Fig. 2

CircDNAJC11 is upregulated in BC tissues and is correlated with patient prognosis. A and B Relative expression of circDNAJC11 in BC and adjacent non-tumor tissues was determined by qRT-PCR. C The ROC curves for the assessment of the diagnostic value of circDNAJC11 in BC. D ISH scores of circDNAJC11 in BC tissues and para-cancer tissues on tissue microarray. E ISH scores of circDNAJC11 in BC tissues from patients at different stages on tissue microarray. F Kaplan–Meier curves for overall survival in different circDNAJC11 expression groups. Patients were divided into a high circDNAJC11 group and a low circDNAJC11 expression group based on the mean circDNAJC11 expression levels in BC tissues. G Representative images of ISH staining of circDNAJC11 on tissue microarray. For A and B, β-actin was utilized as a loading control. Data were presented as mean ± SD in A, B, D, and E. A, B, D, and E were analyzed with Student’s t-test, C was analyzed by ROC curve, and F was analyzed by log-rank test

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