Fig. 2

After CAR-T infusion, patients were monitored for cytokines related to CRS and CAR-T cell expansion. A–C The levels of serum cytokines IL-6, IL-10, and IFN-γ after CART2 infusion. D–E Fold increase and the absolute value of IL-6 in CART1 and CART2 were analyzed by Mann − Whitney U test. The expansion of IL-6 was much higher after CART2 than CART1, although the P value did not reach statistical significance (P = 0.2; P = 0.4). F–G The trends of change in IL-6, IFN-γ, and CAR transgene copies in PB were similar after CART2