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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: The spatiotemporal matching pattern of Ezrin/Periaxin involved in myoblast differentiation and fusion and Charcot-Marie-Tooth disease-associated muscle atrophy

Fig. 8

NFAT signaling is involved in the regulation of myofiber specialization mediated by Ezrin. A, B Typical image of MyHC-I (NOQ) or MyHC-II (MY32) staining in differentiated C2C12 myoblasts treated with Ad-shEzrin with or without Ad-NFATc1, Ad-NFATc2, Ad-shNFATc3 and Ad-shNFATc4. Red fluorescence indicates MyHC-I A or MyHC-II B; DAPI indicates the nucleus. C, D Quantitative assay for MyHC-I-positive and MyHC-II-positive myotubes in the above images. Three independent experiments were performed, n = 3, *P < 0.05 vs. Ad-Null; #P < 0.05 vs. Ad-Null; $P < 0.05 vs. Ad-shEzrin; @P < 0.05 vs. Ad-shEzrin

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Journal of Translational Medicine

ISSN: 1479-5876

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