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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: LINC00543 promotes colorectal cancer metastasis by driving EMT and inducing the M2 polarization of tumor associated macrophages

Fig. 6

LINC00543 blocks the maturation of miR-506-3p. a The expression of miR-506-3p, pre-miR-506-3p, and ppi-miR-506-3p in SH cells. b The relationship between the expression of LINC00543 and Pre-miR-506-3p. c The relationship between the expression of LINC00543 and the expression of miR-506-3p. d The binding regions of LINC00543 to pre-miR-506-3p. e RAP analysis of the expression of pre-miR-506-3p in SH cells. f The expression of pre-miR-506-3p in the nucleus and the cytoplasm in SH cells. g Illustrative model showing that LINC00543 blocked the transportation of pre-miR-506-3p. h RIP analysis of the interaction between XPO5 and pre-miR-506-3p in SH cells. i RIP analysis of the interaction between XPO5 and LINC00543 in SH cells. j Schematic diagram of biotin segment probes. k RAP analysis of the interaction between four segments of LINC00543 and pre-miR-506-3p. l RIP analysis of the interaction between XPO5 and pre-miR-506-3p in cells incubated with antisense nucleotide biotin probes of the three binding regions. m and n The interaction between LINC00543, XPO5, and pre-miR-506-3p were analyzed in cells incubated with the antisense nucleotide biotin probes of the three binding regions

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