J-shape relationship between normal fasting plasma glucose and risk of type 2 diabetes in the general population: results from two cohort studies

Table 3 Threshold effect analysis of FPG and incident diabetes by piece-wise cox regression

	HR (95% CI)	P-value	P for log likelihood ratio test
All populations			< 0.001
FPG < 4.5 mmol/L	1.09 (0.66, 1.79)	0.732
FPG ≥ 4.5 mmol/L	7.75 (6.97, 8.62)	< 0.001
Chinese			< 0.001
FPG < 4.5 mmol/L	1.09 (0.66, 1.79)	0.738
FPG ≥ 4.5 mmol/L	7.3 (6.53, 8.17)	< 0.001
Japanese			0.048
FPG < 5.2 mmol/L	3.22 (0.77, 13.38)	0.109
FPG ≥ 5.2 mmol/L	21.13 (13.17, 33.91)	< 0.001

Statistical analysis method used: piece-wise cox regression analysis and likelihood ratio test
Bold values indicate the statistically significant P values.
Adjusted for age, sex, BMI, SBP, DBP, TC, TG, ALT, smoking, and drinking. All populations additional adjusted for country
T2D type 2 diabetes, FPG fasting plasma glucose, HR hazard ratio, CI confidence interval

ISSN: 1479-5876