Fig. 1

Expression pattern and overall survival (OS) rates of CAPRIN1 in ESCA patients and cell lines. A Comparison of CAPRIN1 expression among EA, ESCC, and normal tissues based on data from the TCGA-ESCA cohort. B Immunohistochemical staining and quantification of Caprin-1 protein in ESCC tissues and adjacent normal tissues. C The protein expression level of Caprin-1 in 14 paired ESCC tissues was examined using Western blot. T, tumor; N, adjacent normal tissues. D CAPRIN1 mRNA expression levels in different ESCA cell lines and fibroblast cultured from esophageal squamous cell carcinoma tissue in the GEO cohort (GSE63941). E OS analysis according to the mRNA expression of CAPRIN1 in ESCC and EA F patients using a Kaplan–Meier plotter. G The ROC curve of CAPRIN1 for the diagnosis of patients with ESCA. * P < 0.05, ** P < 0.01, *** P < 0.001