The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study

Table 2 Effects of menarche age on adiposity indices of participants over time

Reproductive factors	Outcomes	Model 1	P-value ^c	Model 2	P-value ^c
Reproductive factors	Outcomes	Coefficient (95% CI)	P-value ^c	Coefficient (95% CI)	P-value ^c
Menarche age^a (ref: Normal)	BMI (kg/m²)
	Early	1.43 (0.35, 2.50)	0.009	1.18 (0.11, 2.25)	0.030
	Late	− 1.00 (− 1.75, − 0.25)	0.008	− 1.05 (− 1.79, − 0.31)	0.005
	Time	− 0.05 (− 0.09, − 0.006)	0.024	− 0.04 (− 0.09, − 0.001)	0.044
	Time × early	0.08 (− 0.09, − 0.26)	0.343	0.09 (− 0.09, 0.26)	0.327
	Time × late	0.004 (− 0.11,0.12)	0.946	0.006 (− 0.11, 0.12)	0.922
	Waist circumference (cm)
	Early	1.45 (− 1.17, 4.07)	0.278	1.66 (− 0.94, 4.26)	0.211
	Late	− 1.66 (− 3.46, 0.14)	0.070	− 1.72 (− 3.50, 0.07)	0.059
	Time	1.32 (1.19, 1.45)	< 0.001	1.33 (1.20, 1.46)	< 0.001
	Time × early	0.26 (− 0.26, 0.79)	0.316	0.28 (− 0.24, 0.80)	0.295
	Time × late	− 0.08 (− 0.43, 0.27)	0.647	− 0.08 (− 0.42, 0.27)	0.664
	ABSI^b
	Early	− 0.19 (− 0.43, 0.04)	0.111	− 0.05 (− 0.28, 0.17)	0.640
	Late	− 0.02 (− 0.18, 0.15)	0.846	− 0.02 (− 0.17, 0.14)	0.829
	Time	0.20 (0.19, 0.21)	< 0.001	0.21 (0.20, 0.22)	< 0.001
	Time × early	− 0.003 (− 0.06, 0.05)	0.929	− 0.0004 (− 0.05, 0.05)	0.988
	Time × late	0.001 (− 0.04, 0.04)	0.955	0.003 (− 0.03, 0.04)	0.860

BMI Body mass index; ABSI A body shape index; Ref Reference; CI Confidence interval
Model 1: Unadjusted model
Model 2: Adjusted for baseline age, smoking, education, and physical activity status
Time variable means follow-up visits
^aAge at menarche < 11 years, 12–15 years, and ≥ 16 were considered as early, normal, and late menarche, respectively
^bThe results of ABSI are presented by z-scores
^cSignificant p-values (p < 0.05) are bolded

ISSN: 1479-5876