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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Integrated multi-omics analyses and functional validation reveal TTK as a novel EMT activator for endometrial cancer

Fig. 5

Cell subpopulations associated with TTK dysregulation in EC. A the t-SNE plot shows the cell types identified in EC with different colors. B The Violin plot illustrates the expression of classical marker genes in each cluster. C Heatmap showing large-scale CNV profiles of epithelial, ciliated, proliferative cells. Reference CNV levels of endothelial are presented at the top of the plot. The red color represents amplification and the blue represents deletion. D Violin plots depict CDCA8, FAM83D, RACGAP1, and TTK expression across major cell types. E The bar plot demonstrates the KEGG pathway enrichment of genes highly expressed in proliferative cells

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