Table 2 Predicted output from DynaMut, Dynamut2, SDM and MAESTROweb for the stability of SARS-CoV-2 proteins
From: Global landscape of SARS-CoV-2 mutations and conserved regions
Protein | Mutation | Protein structure | Dynamut | Dynamut2 | SDM | MAESTROweb |
|---|---|---|---|---|---|---|
NSP12 | P323L | 7C2K | 1.532 | − 0.18 | 1.18 | − 0.082 |
Spike | D614G | 6VXX | 0.299 | 0.38 | 2.5 | 0.101 |
Envelope | T9I | 7K3G | 0.214 | − 0.12 | 1.1 | 2.902 |
Membrane | A63T | 8CTK | 0.050 | − 0.95 | − 1.53 | 1.351 |
Membrane | I82T | 8CTK | − 0.460 | − 0.5 | − 1.5 | 0.485 |
Membrane | Q19E | 8CTK | − 0.120 | 0.07 | 0.4 | − 0.481 |
Nucleoprotein | D63G | 6VYO | 0.007 | 0.35 | 0.87 | 1.101 |