Table 1 Most common mutations in different SARS-CoV-2 genes
From: Global landscape of SARS-CoV-2 mutations and conserved regions
SARS-CoV-2 region | Mutation | Worldwide (%) | Africa(%) | Asia(%) | Europe(%) | North America(%) | South America(%) | Oceania(%) |
|---|---|---|---|---|---|---|---|---|
NSP1 | S135R | 8.01 | 3.49 | 8.10 | 12.5 | 2.24 | 0.41 | 12.2 |
NSP2 | T85I | 3.94 | 15.6 | 1.79 | 0.64 | 9.27 | 1.05 | 1.48 |
NSP3 | P1228L | 50.0 | 32.2 | 45.1 | 49.0 | 53.6 | 44.1 | 50.1 |
NSP4 | T492I | 70.4 | 52.6 | 60.5 | 73.3 | 69.4 | 59.8 | 77.9 |
NSP5 | P1328 | 30.8 | 23.7 | 25.3 | 34.6 | 27.2 | 39.2 | 21.9 |
NSP6 | T77A | 71.1 | 50.0 | 57.2 | 78.2 | 66.8 | 70.3 | 65.2 |
NSP7 | L71F | 0.22 | 0.14 | 0.25 | 0.13 | 0.20 | 2.8 | 0.03 |
NSP8 | Q24R | 0.70 | 0.18 | 0.06 | 0.44 | 1.29 | 0.12 | 0.03 |
NSP9 | T35I | 0.50 | 0.33 | 0.13 | 0.37 | 0.80 | 0.18 | 0.03 |
NSP10 | T102I | 0.16 | 0.05 | 0.07 | 0.17 | 0.19 | 0.10 | 0.05 |
NSP11 | S6L | 0.16 | 0.27 | 0.08 | 0.16 | 0.19 | 0.10 | 0.04 |
NSP12 | P323L | 99.3 | 95.8 | 98.7 | 99.5 | 99.3 | 99.5 | 97.7 |
NSP13 | P77L | 42.6 | 35.1 | 44.6 | 40.0 | 46.7 | 32.2 | 39.2 |
NSP14 | A394V | 35.1 | 22.5 | 31.7 | 34.9 | 37.0 | 24.9 | 36.5 |
NSP15 | T112I | 8.97 | 5.36 | 10.1 | 13.6 | 2.56 | 1.44 | 12.4 |
NSP16 | R216C | 1.26 | 1.97 | 0.08 | 0.09 | 3.36 | 0.07 | 0.12 |
Spike | D614G | 97.6 | 91.2 | 95.3 | 97.5 | 98.3 | 99.5 | 90.1 |
Orf3a | S26L | 43.1 | 34.4 | 46.0 | 40.5 | 47.2 | 32.8 | 37.0 |
Envelope | T9I | 30.6 | 21.9 | 26.5 | 35.0 | 25.7 | 21.3 | 38.8 |
Membrane | I82T | 47.1 | 42.4 | 47.8 | 45.0 | 52.1 | 34.1 | 40.6 |
Orf6 | D61L | 9.49 | 4.82 | 10.1 | 14.6 | 2.70 | 0.58 | 13.0 |
Orf7a | T120I | 41.4 | 33.3 | 43.9 | 39.4 | 45.3 | 31.2 | 10.5 |
Orf7b | T40I | 39.5 | 30.6 | 33.2 | 39.2 | 41.7 | 33.8 | 40.6 |
Orf8a | S24L | 3.53 | 0.14 | 0.09 | 0.09 | 9.42 | 0.05 | 0.44 |
N | D377Y | 63.2 | 48.8 | 60.4 | 63.2 | 65.6 | 41.7 | – |
Orf9b | T60A | 61.4 | 45.1 | 59.1 | 61.7 | 63.4 | 41.0 | 59.3 |
Orf9c | G50N | 48.8 | 37.9 | 47.4 | 52.8 | 42.4 | – | 51.02 |