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Fig. 11 | Journal of Translational Medicine

Fig. 11

From: Metabolic classifications of renal cell carcinoma reveal intrinsic connections with clinical and immune characteristics

Fig. 11

ACAA2 overexpression inhibits tumor growth in vitro and in vivo and positively correlates with CD8+ T cell immune infiltration. A CCK8 results showing Renca cell proliferation after transfection with control and ACAA2-V101 plasmids. B Representative and statistical results showing the apoptotic changes of Renca cells after transfection with control and ACAA2-V101 plasmids for 48 h. C qPCR results of gene expression changes of Renca cells after transfection with control and ACAA2-V101 plasmids for 48 h. D Tumor volumes of Balb/c murine models subcutaneously transplanted with Renca cells after transfection with control and ACAA2-V101 plasmids. E Representative and statistical results showing tumor infiltrating CD8+ T cells in the vehicle group and ACAA2-Overexpression group. F PD-1 expression of CD8+ T cells in the vehicle group and ACAA2-Overexpression group

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