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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma

Fig. 8

Knockdown of NUDT1 induces antiproliferation and apoptosis in GBM cells. A The vitality of transfected U251 cells was measured through CCK8 assay. B The vitality of transfected U87 cells was measured through CCK8 assay. C, D Knockdown of NUDT1 significantly reduced the quantity of clones in U251 and U87 cells. E–F The EdU assay of U251 and U87 cells after 24 h of transfection with NUDT1, scale bars: 50 μm. G The Calcein-AM/PI staining of U251 and U87 cells after 24 h of transfection with NUDT1, scale bars: 100 μm. H Knockdown of NUDT1 markedly increased the apoptosis rate of U251 and U87 cells. ** P < 0.01

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