Fig. 2

Identification of DEGs and construction of risk model. A, B Screening for mitochondria and oxidative stress-related DEGs based on the TCGA combined GTEx cohort. Red represents upregulated genes with |logFc|> 1 and P < 0.001, black indicates no significantly different genes, and blue illustrates downregulated genes with |logFC|< -1 and P < 0001. C Venn diagram of 110 DEGs screened in 2 DEGs cohorts. D Univariate cox analysis of 110 DEGs. E, F Cross-validation for optimal parameter selection in the LASSO regression model. G Coef values for 5 genes in the risk model