Fig. 6

SPATS2L knockdown enhanced the apoptosis-promoting effect of traditional chemotherapeutics. A IC50 of AML cell lines, THP-1, MV4-11R treated by Ara-c(μM/L), IDA(nM/L), HHT(nM/L). B Protein level of SPATS2L in AML cells treated by Ara-c(μM/L), IDA(nM/L), HHT(nM/L). C Apoptosis of AML cells from THP-cell line among THP-1 scr and THP-1 SPATS2L-sh1, THP-1 SPTS2L-sh2 treated by Ara-c(μM/L), IDA(nM/L), HHT(nM/L), respectively. NS stands for not significant, P < 0.05 *, P < 0.01 **, P < 0.001 ***