Fig. 1
SPATS2L is upregulated in HHT-resistant cell lines. A Integrative analysis of top 50 up-regulated DEGs of our RNA-seq data from HHT-resistant cell lines to identify DEGs commonly shared among different HHT resistance indexes by the venn method. B The Log2 fold change of the 29 commonly upregulated DEGs. C The mRNA and protein expression levels of SPATS2L between HHT-sensitive and resistant cells from MV4-11 by qRT-PCR and western blot, respectively. D The mRNA and protein expression levels of SPATS2L between HHT-sensitive and resistant cells from MOLM13 by qRT-PCR and western blot, respectively. NS stands for not significant, P < 0.05 *, P < 0.01 **, P < 0.001 ***