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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Abnormal signal pathways and tumor heterogeneity in osteosarcoma

Fig. 2

IFITM5 is a potential new driver gene in OS development. A, B Single-cell trajectory analysis using Monocle3, cells colored by tissue origins and pseudotime. C Venn plot show the shared genes among the associated genes in osteogenesis imperfecta, and decreased bone thickness, volume, and length. D Plots of expression for ITIFM and MT2A by pseudotime. E, F UMAP of cell data set branch subsets. Cells are colored by the expression of IFITM5 and MT2A. G Various mutation categories of IFITM5 in Simple ClinVar datasets. H Coding variant mapping and domain annotation for IFITM5

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