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Table 2 Demographics of GBM patients for marker development > 

From: Proteomic analysis predicts anti-angiogenic resistance in recurred glioblastoma

Characteristics

Responder

(n = 7)

Non-responder

(n = 7)

P-value

Age

56.71 ± 6.767

57.43 ± 2.224

0.9218

Gender

Male (n = 6)

Male (n = 2)

 
 

Female (n = 1)

Female (n = 5)

 

Molecular type

 IDH wild type

3

3

 

 MGMT promoter status (methylated/unmethylated/NA)

0/4/3

0/1/6

 

Surgical resection type

 Partial resection

1

3

 

 Gross total resection

6

4

 

 TMZ duration

354.7 ± 98.07

306.9 ± 89.22

0.7244

 Pre-Avastin KPS

60 ± 4.364

50 ± 5.774

0.1922

 Overall survival (days)

828.6 ± 91.21

771.1 ± 172.6

0.7736

 Progression free survival (days)

277 ± 71.79

458 ± 83.35

0.1258

 Avastin dose (mg/kg)

685.7 ± 40.41

595.7 ± 22.24

0.0748

 Initial tumor size (mm3)

20710 ± 5902

28653 ± 6692

0.3909

 Recurred tumor size (mm3)

37549 ± 12,339

23238 ± 6398

0.3235

 TMZ + AVASTIN

n = 7

n = 7

 

 Mono therapy

0

0

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