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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

Fig. 3Fig. 3

Combined starvation and doxorubicin treatment induces differential metabolic reprogramming. a Heatmap visualization of intracellular metabolites profile in MCF-10A and MDA-MB-231 treated with DXR or STS + DXR. Cells were harvested on day 0, day 1 and day 2 after treatment. b Intracellular profile of selected metabolites in MCF-10A and MDA-MB-231 treated with DXR or STS + DXR. Cells were harvested on day 0, day 1 and day 2. *P ≤ 0.05. c Graphical abstract depicting metabolic rewiring in triple-negative breast cancer cells upon combined STS + DXR treatment

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