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Table 1 The significant biological processes enriched by 3′UTR lengthened genes in DN

From: Transcriptomics-proteomics Integration reveals alternative polyadenylation driving inflammation-related protein translation in patients with diabetic nephropathy

Biological process

Count

FDR

Representative Genes

cell-cell adhesion

125

2.92E-09

TWF1, PDLIM1, MYO6, MPRIP, TMOD3, CALD1

macroautophagy

112

2.77E-05

PRKAA1, TOMM22, LAMTOR1, MTDH, DCN

endoplasmic reticulum stress

42

5.45E-05

THBS1, PDIA4, TMX1, TMEM33, UFC1, UFM1

positive regulation of NF-κB signaling

66

5.85E-03

SLC44A2, TMED4, CTNNB1, MYD88, BST2, RELA

ER to Golgi vesicle-mediated transport

78

1.34E-06

LMAN1, PROS1, CUL3, ERGIC1, CTSC, NSF, VAPA

intracellular protein transport

103

3.51E-06

PDCD6, SNX2, ARFIP1, AP3M1, AP2S1, CLTB

vesicle-mediated transport

73

5.46E-06

CLTB, CLINT1, STX12, PLIN3, RAB14, AP3S1

mRNA splicing, via spliceosome

93

1.04E-04

NUDT21, PRPF8, SNRPB2, ELAVL1, DHX15, PPIL3

protein folding

78

2.11E-04

TXNL1, PFDN2, PPIL3, GRPEL1, LTBP4, ERP29

protein stabilization

62

4.57E-04

SUMO1, WFS1, ATP1B3, STX12, PDCD10, BUB3

ubiquitin-dependent protein catabolic

153

2.26E-05

PSMD2, PSME3, PCNP, PCBP2, BUB3, STT3B