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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop

Fig. 1

MiR-26b-5p is a candidate regulator of H. pylori-related GC. A Heatmap of dysregulated miRNAs in GSE108306. B The expression of miR-26b-5p in GC tissues (n = 434) and normal tissues (n = 41) was obtained from the TCGA database. C Kaplan–Meier analysis was conducted to assess the relationship between miR-26b-5p and the survival of GC patients. D MiR-26b-5p expression in GC cell lines and GES1 was detected by qRT-PCR. E MiR-26b-5p expression in 10 pairs of GC tissues and adjacent normal tissues using qRT-PCR. F–G qRT-PCR analysis of miR-26b-5p in GES1 and HGC27 cells infected with H. pylori with indicated MOIs for 6 h or with MOI 100:1 for indicated times. Quantitative data are shown as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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