Fig. 7
From: Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
Suppression of PFKFB3 inhibits IH vessel formation in vivo. A, Diagram of the mouse xenograft models. B, Photographs of tumors in the animal model 14 days after cell implantation. C, Photographs of HE and CD31 staining of hemangiomas and xenografts in animals belonging to the control group, propranolol group, PFK15 group, and combination group. D, Photographs of HE and CD31 staining of hemangiomas and xenografts in animals belonging to the control and shPFKFB3 groups. E, MVD values of the control group, propranolol group, PFK15 group, and combination group. *, P < 0.05; **, P < 0.01; ***, P < 0.001. F, MVD values of the control group and shPFKFB3 group. **, P < 0.01