Subgroups | No of events/participants | HR (95% CI) | P | P for interaction d | RERI (95% CI) e |
---|---|---|---|---|---|
Total samples (N = 30275)a | 0.01 | − 0.06 (− 0.19,0.07) | |||
Types of grains | |||||
Wheat | 4140/6388 | 1.00 | |||
Total rice | 14255/22570 | 0.92(0.89,0.96) | < 0.001 | ||
Coarse cereals | 866/1317 | 0.89(0.82,0.96) | 0.003 | ||
Lifestyle profiles | |||||
Healthy | 4768/8385 | 1.00 | |||
Intermediate | 12187/18268 | 1.10(1.06,1.14) | < 0.001 | ||
Unhealthy | 2306/3622 | 1.14(1.08,1.20) | < 0.001 | ||
Males (N = 13029)b | 0.09 | − 0.06 (− 0.22, 0.10) | |||
Types of grains | |||||
Wheat | 1751/2813 | 1.00 | |||
Total rice | 6036/9681 | 0.89(0.84,0.94) | < 0.001 | ||
Coarse cereals | 349/535 | 0.92(0.82,1.04) | 0.17 | ||
Lifestyle profiles | |||||
Healthy | 2396/4161 | 1.00 | |||
Intermediate | 3810/5791 | 1.08(1.02,1.15) | 0.01 | ||
Unhealthy | 1930/3077 | 1.13(1.06,1.20) | < 0.001 | ||
Females (N = 17246)b | 0.01 | − 0.33 (− 0.62,− 0.04) | |||
Types of grains | |||||
Wheat | 2389/3575 | 1.00 | |||
Total rice | 8219/12889 | 0.96(0.91,1.01) | 0.09 | ||
Coarse cereals | 517/782 | 0.87(0.79,0.97) | 0.01 | ||
Lifestyle profiles | |||||
Healthy | 2372/4224 | 1.00 | |||
Intermediate | 8377/12477 | 1.10(1.05,1.16) | < 0.001 | ||
Unhealthy | 376/545 | 1.10(0.97,1.25) | 0.14 | ||
Age 65–79 years (N = 6789)c | 0.63 | 0.05 (− 0.17, 0.27) | |||
Types of grains | |||||
Wheat | 509/1518 | 1.00 | |||
Total rice | 1709/4988 | 0.83(0.78,0.89) | < 0.001 | ||
Coarse cereals | 101/283 | 0.86(0.75,0.97) | 0.02 | ||
Lifestyle profiles | |||||
Healthy | 657/2180 | 1.00 | |||
Intermediate | 1250/3500 | 1.03(0.96,1.09) | 0.42 | ||
Unhealthy | 412/1109 | 1.09(1.00,1.18) | 0.04 | ||
Age ≥ 80 years (N = 23486)c | 0.04 | − 0.09 (− 0.24, 0.07) | |||
Types of grains | |||||
Wheat | 3631/4870 | 1.00 | |||
Total rice | 12546/17582 | 0.96(0.91,1.01) | 0.09 | ||
Coarse cereals | 765/1034 | 0.90(0.82,1.00) | 0.04 | ||
Lifestyle profiles | |||||
Healthy | 4111/6205 | 1.00 | |||
Intermediate | 10937/14768 | 1.14(1.09,1.20) | < 0.001 | ||
Unhealthy | 1894/2513 | 1.10(1.02,1.17) | 0.01 |