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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Cancer functional states-based molecular subtypes of gastric cancer

Fig. 5

Identification of all cell subtypes in single-cell samples and comparison of stromal cells between three gastric cancer subtypes in GSE183904. A Heatmap displays of 14 cancer functional states for three subtypes of predicted single-cell samples. B, C The tSNE plot of single cells profiled in the presenting work colored by 27 cell clusters and major cell types. D 14 cancer functional states score between three gastric cancer subtypes. E, F The tSNE plot of stromal cells profiled colored by major stromal cell types and three subtypes. G KEGG pathway enriched in marker genes of five stromal cells. H Top 5 marker genes of 5 stromal cells. I Heatmap shows normalized activity of top 5 TF regulons in three subtypes predicted by pySCENIC. J Potential trajectory of iCAF inferred by SCORPIUS. K Kaplan–Meier analysis of high- and low myCAF infiltration in TCGA-STAD. L Comparison of EMT activity of myCAF between three gastric cancer subtypes. M Kaplan–Meier analysis of high- and low iCAF infiltration in TCGA-STAD. N Comparison of iCAF infiltration between three gastric cancer subtypes

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